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临床试验/NCT00427843
NCT00427843已完成不适用

The Influence of a Home Program of Hip Abductor Exercises on Gait Parameters and Muscle Strength in Persons With Knee Osteoarthritis

Queen's University2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2007年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
80
试验地点
2
主要终点
Walking variables: hip and knee abductor and adductor moments

研究概览

简要总结

The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis. Following a hip muscle strengthening program, we hypothesize that participants with knee osteoarthritis will demonstrate decreased loading at the knee joint during walking and greater strength of the hip muscles.

详细描述

Knee osteoarthritis is a common age-related impairment that may progress to cause significant pain and physical disability. Excessive loading at the knee joint is believed to contribute to the progression of knee osteoarthritis. The hip joint and surrounding muscles have been shown to influence the amount of stress occurring at the knee joint during walking. In particular, the hip abductor muscles may have an effect on the knee joint by controlling the position of the pelvis and/or by acting as lateral stabilizers for the knee.

Research suggests that the function of the hip muscles during walking may be decreased in people with knee osteoarthritis and that greater loads may be placed on the knee joint as a result. Thus, interventions aimed at strengthening the hip abductor muscles may be effective for reducing stress on the arthritic knee and slowing the rate of progression of knee osteoarthritis.

The design of the study is a two-group pretest-posttest design using an untreated control group. Thirty-five individuals with medial compartment knee osteoarthritis will be recruited through newspaper advertisements and from the practices of orthopedic surgeons in Kingston, Ontario. Each participant with knee osteoarthritis will be matched with an asymptomatic volunteer for age (+/- 5 years), height (+/- 5 cm), mass (+/- 5 kg) and gender. Participants in the control group will have no clinical or radiographic diagnosis of knee or hip osteoarthritis or rheumatoid arthritis and no history of hip or knee trauma or pain.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
40 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age greater than or equal to 40 years
  • self-reported pain in the knee(s) for most days of the month
  • at least some difficulty in daily function due to knee osteoarthritis
  • radiographic evidence of knee osteoarthritis or documented evidence of cartilage loss in the knee by arthroscopy surgery or magnetic resonance imaging.

排除标准

  • corticosteroid injection into either knee within the previous three months
  • other significant medical problems (including significant heart disease, stroke and active treatment for cancer) that would prevent participants from being able to perform a hip exercise program or to participate in tests of walking performance and hip muscle strength
  • known osteoarthritis or previous trauma affecting one or both hips
  • previous replacement of any joint in the lower extremities.
  • receiving rehabilitation services for knee osteoarthritis or performing a hip strengthening program at the time of testing
  • participants who have had a dual-energy x-ray absorptiometry (DEXA) for bone density analysis or more than one x-ray of the chest, abdomen or hip in the past 6 months

结局指标

主要结局

Walking variables: hip and knee abductor and adductor moments

时间窗: baseline and after 8 weeks

Muscle strength measures: isometric and isokinetic peak torque measures for the hip abductor and adductor muscles

时间窗: baseline and after 8 weeks

次要结局

  • Radiographs: lower limb frontal plane alignment measures - limb alignment in degrees; grading of knee osteoarthritis severity (total score out of 13)(baseline)
  • Speed of performance on the Five-Times-Sit-to-Stand Test(baseline and after 8 weeks)
  • Total score on the WOMAC pain subscale and the WOMAC physical function subscale(baseline and after 8 weeks)
  • Total score obtained for the physical activity scale (PASE)(baseline and after 8 weeks)

研究者

申办方类型
Other

研究点 (2)

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