The Prevalence of Gastroesophageal Reflux Disease in Azerbaijan
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- The prevalence of GERD in Azerbaijan
研究概览
简要总结
To evaluate the prevalence of Gastroesophageal reflux disease in Azerbaijan. It is intended to evaluate the prevalence of the disease in the regions as well as the capital by cluster sampling ,ethitology and to compare the outcomes depending on the geographical location.
详细描述
It is an observational, nationwide study. The GERD questionnaire (1994) requested from Mayo clinic, was received and validated. The questionnaire was translated by 3 individuals from english to azeri and back trasnlated by 3 native english speakers.
Power analysis was performed. The research was presented for the approval to Ethical Committee of Azerbaijan Medical University.
Prior to the actual study, a pilot study with smaller number of participants was performed and the results were evaluated.
Cluster sampling methodology was provided by the statistical department of Azerbaijan Medical University.
110 employees were hired for using a survey in different regions of Azerbaijan. Written consent was obtained from every person evaluated. Statistical ananlysis was performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-80
- •Both genders
- •Regurgitation
排除标准
- •protom pomp inhibitor use
- •antibiotic use in the last 4 weeks
- •upper GI surgery
结局指标
主要结局
The prevalence of GERD in Azerbaijan
时间窗: 1 year
The prevalence of GERD in Azerbaijan was 22.7% with significant female predominance (26.1% vs 15.3%; p\<0.0001). GERD was defined in 17 % for ages below 35; 22.7 % for 36-55 and 38.5 % for those who are above 56 that, accordingly, indicating that GERD becomes significant as age increases (p\<0.0001). Reflux was observed in 18.1% of normal weight respondents (BMI 18.6-24.9), 25.6% of overweight (BMI 25-29.9), and in 30.4% of obese (BMI\>30) individuals (p=0.001). Regarding marital status, the prevalence was the lowest in the single subjects' group (17%), close to average in the married group (23.8%), and the highest (41.7%) in divorced/widowed cases (p=0.003). Stress was significantly affecting GERD distribution, affecting 59.4% of all respondents (p\<0.004).
GERD questionnaire (GERD) of Mayo case 1998- 019
时间窗: 1 year
Observational study
次要结局
未报告次要终点
研究者
Sevda Aghayeva
principal investigator
Azerbaijan Gastroenterology and Hepatology Association