A Pilot Efficacy Trial of a Computer Decision Support System Compared to Usual Care for Depression Treatment in Primary Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- Mean change from baseline in the 17-item Hamilton Rating Scale for Depression (HRSD) Score
研究概览
简要总结
The purpose of this study was designed to test the feasibility and effectiveness of implementing a Computerized Decision Support System for depression (CDSS-D) during acute care in a primary care setting.
详细描述
The research project was designed to test the feasibility and effectiveness of implementing a Computerized Decision Support System for depression (CDSS-D) during acute care in a primary care setting. The basic experimental design was a two-group, two-site study design. Three different clinics with a total of 4 primary care physicians agreed and provided informed consent and participated in the study. Half of the physicians used the CDSS-D to treat patients with MDD and the other half provided Usual Care (UC) treatment.
The intervention, CDSS-D, incorporated a pre-existing depression treatment algorithm (Texas Medication Algorithm Project for Depression, Trivedi et al) with computer decision support programming, providing the treatment group physicians with a computerized algorithm.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Outpatients aged 18 and over
- •Met Criteria for Non-Psychotic Major Depressive Disorder
- •Had a baseline HRSD-17 score of at least 14
排除标准
- •Patients with a current Axis I diagnosis of somatization disorder, anorexia nervosa, bulimia, or obsessive-compulsive disorder
- •Patients with current alcohol or substance dependence
- •Women with a positive pregnancy test or who are lactating
- •Women of child-bearing potential who are not practicing a clinically accepted method of contraception
- •Patients with general medical conditions that contraindicate antidepressant medications
- •Patient whose clinical status requires inpatient or day hospital treatment
研究组 & 干预措施
CDSS-D
Computer Decision Support System for Depression (CDSS-D) - This arm provided physicians with a computerized treatment algorithm and a decision support system to treat their patients suffering Major Depressive Disorder
干预措施: Computerized Decision Support System for Depression (CDSS-D) (Other)
UC
Usual Care (UC) - This group of physicians treated their patients suffering from Major Depressive Disorder with their standard treatment as usual, and received no algorithm support with regard to treatment decisions
干预措施: Usual Care (UC) (Other)
结局指标
主要结局
Mean change from baseline in the 17-item Hamilton Rating Scale for Depression (HRSD) Score
时间窗: 24 weeks
次要结局
- Mean change from baseline on the 16-item Quick Inventory of Depressive Symptomatology - Self Report (QIDS-SR-16)(24 weeks)
- Mean change from baseline on the 30-item Inventory of Depressive Symptomatology - Clinician's version (IDS-C-30)(24 weeks)