ASSOCIATION BETWEEN THE APPLICATION OF PARASTERNAL BLOCKADE AND SERUM LACTATE LEVEL IN TRANS- AND POST-ANESTHETIC STAGES IN CARDIAC SURGERY
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 86
- 试验地点
- 2
- 主要终点
- Lactate serum levels
研究概览
简要总结
Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.
详细描述
An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Lactate serum levels
时间窗: 24 Hours
Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.
次要结局
未报告次要终点
研究者
Clotilde Fuentes-Orozco
Investigador Principal
Instituto Mexicano del Seguro Social
