Predicting Postoperative Pulmonary Complications In Obstructive Sleep Apnea Patients; Multicentre, Prospective, Observational Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- postoperative pulmonary complications
研究概览
简要总结
It is known that perioperative respiratory complications occur more often in obstructive sleep apnea syndrome (OSAS) patients during general anesthesia. Although there are prospective RCTs in this area, the need for further and larger studies remains due to the heterogenity of the results. Moreover, the incidence of postoperative pulmonary complications in OSAS patients undergoing surgery in Turkey and the predictive factors affecting the respiratory adverse events are uncertain. Therefore, in this prospective observational cohort study, it was aimed to determine the incidence of postoperative pulmonary complications and the predictor factors associated with patient, anesthesia and surgery in surgical patients with a confirmed or highly suspected OSAS diagnosis undergoing general anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18-65 years
- •ASA physical status I-III
- •Preoperative OSAS diagnosis (with polysomnography or STOP-BANG questionnaire score)
- •Surgeries performed under general anesthesia
- •Endotracheal intubation facilitated by neuromuscular blockers
排除标准
- •ASA physical status IV or V
- •Planned admission to the ICU after surgery
- •Cardiac Surgery
- •Non-operating room anesthesia
- •Neuromuscular disease
- •Emergency or re-operational procedure
- •Laryngectomy
- •Pneumonectomy
- •Invasive airway access
- •Outpatient surgery
结局指标
主要结局
postoperative pulmonary complications
时间窗: Postoperative day 1, 2, 7 and 30.
The rate of postoperative hypoxia (respiratory failure), atelectasis, pulmonary edema /embolus, aspiration, bronchospasm, respiratory infection / pneumonia, pleural effusion, pneumothorax, respiratory arrest will be measured
次要结局
- Mortality(Postoperative day 30.)
- Non-invasive/invasive mechanical ventilation requirement(Postoperative day 1, 2, 7 and 30.)
- Intensive care unit admission(Postoperative day 1, 2, 7 and 30.)
- Predictive factors(Postoperative day 1, 2, 7 and 30.)
研究者
Demet Laflı Tunay
Assistant Professor
Cukurova University