Comparing Intrathecal Morphine and Erector Spinae Plane Regional Anesthesia Against Intrathecal Morphine Alone for Post-Cesarean Section Pain
试验速览
- 阶段
- 4 期
- 状态
- 暂停
- 入组人数
- 100
- 主要终点
- post-operative opioid analgesic medication
研究概览
简要总结
The objective of the study is to optimize post-operative analgesia and improve patient satisfaction while reducing total opioid consumption after cesarean section
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Adults unable to consent
- •Individuals <18 years of age at time of admission
- •Individuals taking anticoagulant medications
- •Significant co-morbid disease of pregnancy (including: gestational diabetes and significant abnormal placentation)
- •Pre-existing chronic pain or pain disorder diagnosis
- •Conversion from neuraxial to general anesthesia
- •Prisoners
研究组 & 干预措施
erector spinae plane block
participants will be in this group for up to 9 months and receive erector spinae plane (ESP) block
干预措施: erector spinae plane block (ESP) (Procedure)
erector spinae plane block
participants will be in this group for up to 9 months and receive erector spinae plane (ESP) block
干预措施: Duramorph (Drug)
erector spinae plane block
participants will be in this group for up to 9 months and receive erector spinae plane (ESP) block
干预措施: Ropivacaine (Drug)
erector spinae plane block
participants will be in this group for up to 9 months and receive erector spinae plane (ESP) block
干预措施: Bupivacaine Injection (Drug)
standard of care
participants in this group will receive the standard of care treatment and will be in this group for up to 9 months.
干预措施: Duramorph (Drug)
standard of care
participants in this group will receive the standard of care treatment and will be in this group for up to 9 months.
干预措施: Ropivacaine (Drug)
standard of care
participants in this group will receive the standard of care treatment and will be in this group for up to 9 months.
干预措施: Bupivacaine Injection (Drug)
结局指标
主要结局
post-operative opioid analgesic medication
时间窗: up to 24 hours
measurement (milligrams)
次要结局
- change in post-operative pain medication by visual analog scale(baseline, up to 24 hours)
- number of minutes to first use of rescue medication(up to 24 hours)
- obstetric quality of recovery scale(up to 24 hours)
研究者
Reine Zbeidy
Associate Professor of Clinical Anesthesiology
University of Miami