Faster Peritoneal Solute Transfer Rate and Survival in a Pre-APD and Icodextrin Peritoneal Dialysis Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 430
- 主要终点
- The relationship between fast PSTR and worse outcome in PD.
研究概览
简要总结
A fast peritoneal solute transfer rate (PSTR) has been linked to worse survival especially in continuous ambulatory peritoneal dialysis (PD) cohort. In more recent cohorts, where automated PD and icodextrin were more widely used, this association disappears. The current study intended to clarify whether fast PSTR is related to worse outcome in this single center cohort with minimal use of APD and no icodextrin and otherwise modern management practice. Our study found that baseline PSTR predicted patient outcome in univariate survival analysis but not in multivariate analysis. The relationship between comorbidity and faster baseline PSTR may partly explain it.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients are Han Chinese;
- •Patients prepare for dialysis in our center, and start PD within 3 months after abdominal catheterization;
- •Patients successfully complete the first peritoneal equilibration test(PET);
- •Follow up regularly in our PD center.
排除标准
- •Patients from hemodialysis to peritoneal dialysis;
- •Patients who need peritoneal dialysis due to transplant-renal loss;
结局指标
主要结局
The relationship between fast PSTR and worse outcome in PD.
时间窗: The data collection time period of the study is over 10 years.
Baseline PSTR predicted patient outcome in univariate survival analysis but not in multivariate analysis. The relationship between comorbidity and faster baseline PSTR may partly explain it.
次要结局
未报告次要终点