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临床试验/CTRI/2023/12/060947
CTRI/2023/12/060947尚未招募1/2 期

Effects of grip strengthening exercises on post-operative breast carcinoma patients.

Dr. Vaishnavi Joshi1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年1月5日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
• Patient-Rated Wrist/Hand Evaluation (PRWHE)(15 items)

研究概览

简要总结

TITL Effects of grip strengthening exercises on hand functions in post-operative breast carcinoma patients.

 INTRODUCTION :-

Breast cancer is a type of cancer that begins in the breast tissue. It occurs when abnormal cells in the breast grow and multiply uncontrollably, forming a tumor that can invade nearby tissues and spread to other parts of the body. Breast cancer is the most common cancer among women worldwide, with an estimated 2.3 million new cases diagnosed in 2020 alone.

There are several types of breast cancer, including ductal carcinoma in situ, invasive ductal carcinoma, and invasive lobular carcinoma. Risk factors for breast cancer include being female, increasing age, family history of breast cancer, certain gene mutations, personal history of breast cancer or certain non-cancerous breast conditions, and exposure to estrogen. Breast cancer can be diagnosed through a combination of physical exams, imaging tests, and biopsies.

Treatment for breast cancer depends on several factors, including the type and stage of the cancer, the patient’s age and overall health, and the patient’s preferences. Treatment options may include surgery, radiation therapy, chemotherapy, hormonal therapy, targeted therapy, or a combination of these approaches .

Breast cancer screening, early detection, and treatment have improved significantly over the past few decades, leading to better outcomes for many patients. However, breast cancer remains a significant public health concern, and ongoing research is needed to improve prevention, diagnosis, and treatment.

Breast cancer is one of the most commonly diagnosed cancers and a leading cause of cancer-related deaths in women worldwide. The epidemiology of breast cancer includes the incidence, mortality, and prevalence rates of the disease, as well as its risk factors and distribution across different populations.

In 2020, there were an estimated 2.3 million new cases of breast cancer globally, making it the most commonly diagnosed cancer among women worldwide3. The incidence of breast cancer varies across different regions and countries, with higher rates reported in developed countries such as the United States, Canada, and Europe, and lower rates reported in less developed regions such as Africa and South Asia.

The mortality rate of breast cancer has been declining in many countries, likely due to improvements screening, early detection, and treatment. However, breast cancer still accounts for a significant proportion of cancer-related deaths among women. In 2020, there were an estimated 685,000 deaths from breast cancer worldwide.

Breast cancer and its treatment can have significant physical and emotional effects on a patient’s activities of daily living (ADLs). ADLs refer to the basic self-care activities that individuals perform on a daily basis, including bathing, dressing, grooming, feeding, toileting, and mobility.

Breast cancer surgery, such as a mastectomy or lumpectomy, can impact a patient’s ability to perform certain ADLs, particularly in the immediate postoperative period. For example, patients may experience pain, swelling, and limited range of motion in the affected arm, which can make it difficult to perform tasks such as dressing and grooming.

In addition, radiation therapy and chemotherapy can cause fatigue, nausea, and other side effects that may interfere with a patient’s ability to perform ADLs. Emotional distress and anxiety are also common among breast cancer patients, which can affect their motivation and ability to carry out ADLs .

Inclusion criteria:

Women  who have undergone surgical management for breast cancer

Age 18 to 70

 Exclusion criteria:

Have recent history of hand, wrist, or forearm injuries

other impairments of upper extremity

Outcome measures:

Patient-Rated Wrist/Hand Evaluation (PRWHE)(15 items)

Jebsen Taylor Hand function test

Hand grip dynamometer

Pinch gauge dynamometer

Visual Analogue Scale

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
Female

入选标准

  • women who underwent surgical management for breast cancer.

排除标准

  • Have recent history of hand, wrist, or forearm injuries.
  • 2.other impairments of upper extremity.

结局指标

主要结局

• Patient-Rated Wrist/Hand Evaluation (PRWHE)(15 items)

时间窗: post op day 1 | day of follow up day 12

• Jebsen Taylor Hand function test

时间窗: post op day 1 | day of follow up day 12

• Hand grip dynamometer

时间窗: post op day 1 | day of follow up day 12

• Pinch gauge dynamometer

时间窗: post op day 1 | day of follow up day 12

• Visual Analogue Scale

时间窗: post op day 1 | day of follow up day 12

次要结局

未报告次要终点

研究者

发起方
Dr. Vaishnavi Joshi
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Vaishnavi Joshi

Sunandan divatia school of science

研究点 (1)

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