ATM Variants in Radiotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- to determine baseline incidence of variant alleles in ATM
研究概览
简要总结
The purpose of this study is to compare the baseline incidence of variant alleles in the ATM and/or other DNA repair genes present in the Native American population versus the non-Native American population. It is thought that a higher baseline incidence of the variant alleles in the ATM gene may correlate to higher rates and higher grades of radiation toxicities noted in the Native American population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Indication for radiotherapy.
- •Ability or desire to donate a blood sample and be followed closely for radiation toxicities
排除标准
- 未提供
结局指标
主要结局
to determine baseline incidence of variant alleles in ATM
时间窗: one blood draw
to determine the baseline incidence of variant alleles in ATM resent in the population of Native americans with cancer who are undergoing radiation therapy to a similar group of non-native americans who have undergone or are undergoing raditohterapy
次要结局
- to compare the baseline incidence of variant alleles in ATM(one blood draw)
