跳至主要内容
临床试验/NCT00214227
NCT00214227已完成不适用

ATM Variants in Radiotherapy

University of Wisconsin, Madison1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2007年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
to determine baseline incidence of variant alleles in ATM

研究概览

简要总结

The purpose of this study is to compare the baseline incidence of variant alleles in the ATM and/or other DNA repair genes present in the Native American population versus the non-Native American population. It is thought that a higher baseline incidence of the variant alleles in the ATM gene may correlate to higher rates and higher grades of radiation toxicities noted in the Native American population.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Indication for radiotherapy.
  • Ability or desire to donate a blood sample and be followed closely for radiation toxicities

排除标准

  • 未提供

结局指标

主要结局

to determine baseline incidence of variant alleles in ATM

时间窗: one blood draw

to determine the baseline incidence of variant alleles in ATM resent in the population of Native americans with cancer who are undergoing radiation therapy to a similar group of non-native americans who have undergone or are undergoing raditohterapy

次要结局

  • to compare the baseline incidence of variant alleles in ATM(one blood draw)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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