Effects of Upper Extremity Aerobic Exercise Training on Functional Exercise Capacity in Patients With Pulmonary Arterial Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Functional exercise capacity (Oxygen consumption measurement during test)
研究概览
简要总结
Decreased exercise capacity, peripheral muscle strength and quality of life and increased dyspnea and fatigue perception is prevalent in patients with pulmonary arterial hypertension. It was demonstrated exercise training has beneficial effects in patients with pulmonary arterial hypertension. However, no study investigated the effects of upper extremity aerobic exercise training, therefore effects of upper extremity aerobic exercise training on outcomes in patients with pulmonary arterial hypertension.
详细描述
Patients were diagnosed with pulmonary arterial hypertension according to the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of f the European Society of Cardiology (ESC) and European Respiratory Society (ERS). Primary outcome measurement was exercise capacity, secondary outcomes were respiratory and peripheral muscle strength, physical activity, quality of life, fatigue, dyspnea and depression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically stable
- •Under standard medication
- •Group 1 pulmonary arterial hypertension patients
- •Having no exacerbation or infection
排除标准
- •Cognitive disorders
- •Orthopedic and neurological problems
- •Pneumonia or acute infection
- •Stage 4 heart failure
- •Having no comorbidity to avoid performing evaluation and training
研究组 & 干预措施
Training Group
Intervention:Training group will receive upper extremity aerobic exercise training using arm ergometer and breathing exercises.
干预措施: Upper extremity aerobic exercise training (Other)
Control Group
Sham: Control group will receive alternative upper extremity exercises and breathing exercises.
干预措施: Alternative upper extremity exercises (Other)
结局指标
主要结局
Functional exercise capacity (Oxygen consumption measurement during test)
时间窗: 6 weeks
Six minute walk test (6MWT)
次要结局
- Generic quality of life(6 weeks)
- Maximum inspiratory and expiratory muscle strength (MIP, MEP)(6 weeks)
- Peripheral muscle strength(6 weeks)
- Pulmonary functions(6 week)
- Physical activity(6 weeks)
- Dyspnea(6 weeks)
- Fatigue(6 weeks)
- Depression(6 weeks)
研究者
Meral Boşnak Güçlü
Assoc. Prof
Gazi University