跳至主要内容
临床试验/NCT03001973
NCT03001973招募中不适用

High Quality Evidence of Chinese Lupus Nephritis (HELP)

Sun Yat-sen University2 个研究点 分布在 1 个国家目标入组 5,000 人开始时间: 2013年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
5,000
试验地点
2
主要终点
All-cause mortality and cardiovascular mortality of LN patients

研究概览

简要总结

The investigators are registering LN patients at recruited hospitals and developing a LN database in China. Patients will be follow-up every year, and both baseline and follow-up information will be entered into the registration system.

详细描述

The investigators are registering Lupus nephritis (LN) and developing a LN database in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education etc.), clinical characteristics (including systolic blood pressure, diastolic blood pressure, and lab measurements of whole blood, serum, urine etc.), complications, drug information at the baseline will be collected. Patients will be follow-up every year, the demographic and clinical characteristics, complications; drug information of patients will be collected at each visit. We will also record the outcome at each visit, such as mortality (including all-cause mortality and cardiovascular disease mortality), end-stage renal disease (ESRD) or serum creatinine doubling. The patient survival and renal survival will be compared using the LN database.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
14 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who diagnosis as lupus nephritis

排除标准

  • 未提供

研究组 & 干预措施

LN patients

Patients diagnosis as lupus nephritis

干预措施: No Intervention (Other)

结局指标

主要结局

All-cause mortality and cardiovascular mortality of LN patients

时间窗: 10years

A composite renal outcome of LN patients

时间窗: 10years

The composite renal outcome defined as doubling of serum creatinine and ESRD (defined as initiation of dialysis or kidney transplantation).

次要结局

未报告次要终点

研究者

发起方
Sun Yat-sen University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Xue Qing Yu

Professor

Sun Yat-sen University

研究点 (2)

Loading locations...

相似试验

High Quality Evidence of Chinese Lupus Nephritis... | 临床试验