The Effect of Altered Gravity Condition on Postural Control
试验速览
- 阶段
- 不适用
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- spinal excitability, expressed by H-Reflexes
研究概览
简要总结
The scientific goal of this experiment is to evaluate changes in balance control in response to microgravity during reactive balance tasks. For that purpose, kinematic and neuromuscular parameters under microgravity are compared to normal gravity conditions. To induce postural responses among the test subjects, an electromagnetic maneuverable postural platform will be used in order to randomly elicit perturbations. Postural reactions will be quantified by means of mechanical and electromyographic data. In Addition, peripheral nerve stimulation will be used to assess the spinal excitability by means of H-reflex recordings. H-reflex measurements were chosen as they allow reliable information about inhibitory and facilitatory mechanisms taking place at the spinal level.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers (men or women)
- •Aged from 21 to 65
- •Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC)
- •Who accepted to take part in the study
- •Who have given their written stated consent
- •Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection.
排除标准
- •Person who took part in a previous biomedical research protocol, of which exclusion period is not terminated
- •Person with medical history of neurological disorders
- •Person with medical history of musculoskeletal disorders of the lower limbs, especially of the ankle and knee joint.
- •Pregnant women
研究组 & 干预措施
in balance control in response to microgravity
to evaluate changes in balance control in response to microgravity during reactive balance tasks compared to normal gravity.
干预措施: electromagnetic maneuverable postural platform (Device)
in balance control in response to microgravity
to evaluate changes in balance control in response to microgravity during reactive balance tasks compared to normal gravity.
干预措施: Parabolic flight (Other)
in balance control in response to microgravity
to evaluate changes in balance control in response to microgravity during reactive balance tasks compared to normal gravity.
干预措施: balance control measurements (Other)
结局指标
主要结局
spinal excitability, expressed by H-Reflexes
时间窗: baseline
balance skill, expressed by the postural sway in mm
时间窗: baseline
neuromuscular activity, expressed by the Electromyograpy (EMG)-amplitudes
时间窗: baseline
次要结局
未报告次要终点