Activated cell metabolism in post-covid-19-fatigue and its modulation by mindfulness-based multimodal therapies

Klinik für Psychosomatische Medizin und Psychotherapie0 个研究点目标入组 118 人开始时间: 2022年8月5日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1) Post-Covid patients
•Inclusion Criteria:
•Patients between the ages of 18 and 80 who were infected with Covid-19 at least 3 months ago and who suffer from typical post-Covid symptoms of fatigue-like symptoms and limited physical performance.
•Other post-Covid symptoms such as shortness of breath, headaches, smell and taste disorders, subjectively experienced cognitive deficits, depressive or anxious symptoms or sensory disorders.
•2) FMS patients
•Inclusion Criteria:
•Patients between the ages of 18 and 80 years with a confirmed diagnosis by a neurologist or rheumatologist via FMS according to the 2010 ACR criteria.
•3) Control group to post-Covid group
•People who have recovered from an infection with SARS-CoV-2 and continue to have so-called post-Covid symptoms after this infection and receive medical support in the clinic, but no specialized mindfulness-based therapy for 4 weeks. The patient group acts as a control with regard to the success of the therapy in order to rule out that the symptoms improved purely for reasons of time. These control patients also take part in two survey days, the time interval is organized similarly to the patient group with a break of 4 weeks.

•1) Post-Covid patients
•Excluded are people who are acutely addicted and show acute suicidal tendencies, who have psychotic disorders who require long-term medication that has a proven influence on the oxidative cell metabolism (e.g. levodopa for the treatment of Parkinson's or medications containing N-acetylcysteine ??and other antioxidants such as vitamin C), are demented, do not have sufficient knowledge of German, are not sufficiently fit to carry out the study program and cannot easily reach the Nuremberg Clinic from their place of residence.
•2) FMS patients
•Other rheumatological or orthopedic differential diagnoses that could explain the pain.
•Abnormalities in routine blood tests
•Psychiatric disorders
•Polyneuropathy
•Cancer (in the last 5 years)
•Drugs (nicotine) or alcohol abuse

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