NCT02585739已完成不适用
Cluster Headache and SPINK-1 Gene
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- SPINK1 genotyping
研究概览
简要总结
Cluster headache (CH) is a rare, excruciating primary headache disorder. A genetic basis has been suggested by family and twin studies, but the mode of transmission seems to vary and the amount of heritability is unclear.
The number of genetic association studies investigating variants implicated in the pathophysiology of CH is limited. The HCRTR2 1246G > A and the ADH4 925A > G polymorphisms have been associated with CH. The former has been confirmed and may affect the hypothalamic hypocretin system. The aim of the present study was to investigate the possible link between SPINK 1 gene and cluster headache.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •People aged 18 or over
- •Patient consulting in Marseille's or Nice's Pain departments
- •Patient agreeing to participate to the research study
- •Patient with health insurance
排除标准
- •People aged under 18
- •Patient refusing to participate to the research study
- •Patient with deprivation of liberty
结局指标
主要结局
SPINK1 genotyping
时间窗: 2 months
次要结局
未报告次要终点
研究者
研究点 (1)
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