The influence of ambient temperature changes on inflammatory markers in blood.
试验速览
- 阶段
- 不适用
- 状态
- Not Applicable
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Examination of patients’ peripheral blood serum activity of arylsulfatase, acid
研究概览
简要总结
This study will assess the impact of postexercise sauna treatment and cold water immersion on inflammation markers in blood. The organism reaction to ambient temperature changes is regulated by a number of substances. Detailed analysis of changes in the concentration of selected interleukins, C-reactive protein and the activity of lysosomal enzymes and protease inhibitor, the substances potentially involved in the body’s reaction to ambient temperature changes, can identify factors that play a key role in the mechanism of adaptation to thermal stress
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Male
入选标准
- •healthy persons, non-smokers.
排除标准
- •Persons treated for any co-morbidities, smoking cigarettes and using a diet that could affect inflammation rates were excluded from the study.
结局指标
主要结局
Examination of patients’ peripheral blood serum activity of arylsulfatase, acid
时间窗: The experimental material was venous blood taken from the basilic vein into vacuum test | tubes three times for each participant (before exercise, 2 and 20 minutes after exercise): for | blood serum (clot activator and gel separator).
phosphatase, cathepsin D, alpha1-antitrypsin.
时间窗: The experimental material was venous blood taken from the basilic vein into vacuum test | tubes three times for each participant (before exercise, 2 and 20 minutes after exercise): for | blood serum (clot activator and gel separator).
次要结局
- Examination of patients’ peripheral blood serum concentration of interleukin 6 (IL-6), interleukin 10 (IL-10), tumor necrosis factor α (TNF-α) and transforming growth factor β1 (TGF-β1) and C-reactive protein (CRP)