Functional Connectivity In Relation To Proprioception and Sensorimotor Recovery in Stroke Patients (Feasibility Study)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Preliminary study to measure the brain mechanisms of cognitive multisensory rehabilitation
研究概览
简要总结
The purpose now is to:
- identify brain connections related to proprioception to have a better understanding of differences between people with stroke and healthy persons
- evaluate how these brain connections will change in people with stroke when they are engaged in 6-week cognitive multisensory rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion criteria for healthy subjects are:
- •medically stable;
- •18 - 99 years of age;
- •able to hear the instructions given during the study
- •Inclusion criteria for stroke patients are:
- •at least 6 months post-stroke;
- •medically stable;
- •18 - 99 years of age;
- •subcortical or cortical infarct confirmed with MRI;
- •Mini-mental State Exam > 24/30 (Folstein et al., 1975);
- •able to hear the instructions given during the study;
- •able to comprehend the instructions given during the study;
- •able to commit time to participate in a 6-12-weeks rehabilitation program
排除标准
- •having ever experienced a stroke or another brain injury or illness related to the brain that has lasting effects or effects experienced at the moment of recruitment;
- •severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
- •contractures in tested arm that hinder persons from keeping the outstretched arm in a relaxed position;
- •interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
- •exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
- •pregnant or nursing mother;
- •adults lacking capacity to consent
研究组 & 干预措施
Cognitive multisensory rehabilitation
The treatment group will receive the cognitive multisensory rehabilitation that uses motor imagery and sensory discrimination exercises
干预措施: Cognitive multisensory rehabilitation (Other)
结局指标
主要结局
Preliminary study to measure the brain mechanisms of cognitive multisensory rehabilitation
时间窗: 8 weeks
The robots will be used for research in healthy adults and stroke patients in the proposed studies below and are designed to mimick the exercises given during cognitive multisensory rehabilitation. The robots have been tested and cleared by the 3T safety committee at the CMRR, U of M. The first objective is a feasibility study to investigate the brain mechanisms of cognitive multisensory rehabilitation, through use of the robot in the 3T scanner at the U of M in healthy participants with stroke. Changes in brain function will be measured in individuals with stroke who will receive 8 weeks of therapy.
次要结局
未报告次要终点