NCT01886417已完成不适用
Electromyography Study of Lip Muscles During Auditory Verbal Hallucinations Without Subvocalization in Patients With Schizophrenia
University Hospital, Grenoble1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2009年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Labial EMG activity during auditory verbal hallucination
研究概览
简要总结
Auditory verbal hallucinations (AVHs) are speech perceptions in the absence of a relevant external stimulation. Some accounts of AVHs claim that a deficit in inner speech monitoring would cause the verbal thoughts of the patient to be perceived as external voices resulting in AVHs.
In order to examine whether AVHs correspond to self-generated inner speech, the present study aims at collecting speech muscle activity during covert AVHs (without articulation), overt speech and rest. Surface electromyography (sEMG) is used on schizophrenia patients and control subjects to detect any speech muscle activity during AVH.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy controls:
- •must be more than 18 years and less than 60 years old
- •pre-inclusion medical examination
- •must have signed consent form
- •must be able to read stimuli on a screen
- •Schizophrenia patients:
- •must be more than 18 years and less than 60 years old
- •pre-inclusion medical examination
- •must have signed consent form
- •must be able to read stimuli on a screen
- •diagnosed with a schizophrenia disorder according to DSM-IV TR (diagnostic and statistical of mental disorders) (PANSS item P3 greater than 4)
- •prior evaluation of the secondary effects of any medication via Barnes and AIMS scales
- •affiliated with the French social security
- •if under guardianship, must have additional consent form signed by guardian
排除标准
- •Healthy controls:
- •if aged less than 18 years or more than 60 years
- •diagnosed with any psychiatric disorder
- •with any language disorder (aphasia, SLI, dysarthria, stuttering, etc.)
- •with auditory impairment
- •pregnant, parturient, breast-feeding
- •Schizophrenia patients:
- •if aged less than 18 years or more than 60 years
- •significant secondary effects of antipsychotic medication, measured with the Barnes and AIMS scales
- •with a neurodegenerative disease
- •with any language disorder (aphasia, SLI, dysarthria, stuttering, etc.)
- •with auditory impairment
- •pregnant, parturient, breast-feeding
结局指标
主要结局
Labial EMG activity during auditory verbal hallucination
时间窗: up to 3 years
次要结局
未报告次要终点
研究者
研究点 (1)
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