临床试验/NCT07105371

NCT07105371已完成1 期

Patients With ALS and Other Motor Discorders Will be Treated With Mesenchymal Cell Exosome Solution

The Foundation for Orthopaedics and Regenerative Medicine1 个研究点分布在 1 个国家目标入组 18 人开始时间: 2024年7月14日最近更新: 2025年8月22日

干预措施

试验速览

阶段: 1 期
状态: 已完成
发起方
入组人数: 18
试验地点: 1
主要终点: ALSFRS-R Results

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Patients with ALS and other Motor Discorders will be treated with mesenchymal cell exosome solution.

详细描述

Single Arm non-controlled study. Patients are prospectively evaluated then treated. Outcomes are tracked after treatment.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients will need a diagnosis established by a neurologist. Patients must be able to provide informed consent, or have a guardian who does. They must be able to travel to the site of treatment.

排除标准

•Patients were excluded from the trial if they were pregnant or had active cancer at the screening consultation.

研究组 & 干预措施

Treatment Group (AlloEx)

Experimental

干预措施: AlloEx exosomes (Biological)

结局指标

主要结局

ALSFRS-R Results

时间窗: from enrollment until 6 months after treatment

次要结局

未报告次要终点

研究者

发起方

The Foundation for Orthopaedics and Regenerative Medicine

申办方类型

Other

责任方

Sponsor

研究点 (1)

Loading locations...

相似试验

已完成

不适用

New Therapeutic Strategy in ALS Based on Metabolic Status and Associated Metabolic Pathways.Amyotrophic Lateral Sclerosis

NCT03984708University Hospital, Tours9

已完成

不适用

Amyotrophic Lateral Sclerosis (ALS) Tissue Donation ProgramAmyotrophic Lateral SclerosisNeurodegenerative DiseaseMotor Neuron Disease

NCT00716131Drexel University College of Medicine205

招募中

不适用

A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS

NCT06917924A.O.U. Città della Salute e della Scienza200

No Longer Available

不适用

Treatment of Lambert-Eaton Myasthenic Syndrome (LEMS) With 3, 4 DAPLambert Eaton Myasthenic Syndrome (LEMS)

NCT01378546Louis H. Weimer, MD

已完成

1 期

Escalated Application of Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis PatientsMotor Neuron Disease

NCT02987413Hospital e Maternidade Dr. Christóvão da Gama3