Effect of Hydroxyurea on fetal hemoglobin(HbF) in sickle cell anemia and its impact on splenic function and biochemical parameters in a tertiary care hospital - NI

Sura. Amarendar0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月1日

试验速览

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•Painful crises (in the past 12 months, there were more than three occurrences)
•More than two blood transfusions in the last 12 months. The term painful crisis refers to an acute painful occurrence that necessitates the use of oral or injectable analgesics and lasts for at least 4 hours when no other reason can be found to account for the symptom
•Patients under hydroxyurea therapy will be approached to enrol in this study to assess splenic hypofunction

•children under the age of 3years and adults over 60years of age
•concomitant diseases such as neutropenia and thrombocytopenia may have increased the hydroxyureas toxicity
•Patients who are participating in a particular program or study that could have had an impact on their clinical or haematological state
•renal dysfunction is indicated by blood creatinine levels that are 1.5 time or more above normal

发起方

Sura. Amarendar