NCT06393309已完成不适用
Investigation of Long-term Outcome of Levetiracetam and Valproate in Treatment of Idiopathic Generalized Epilepsy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 169
- 试验地点
- 1
- 主要终点
- Seizure free rate
研究概览
简要总结
This study aimed to compare the long-term efficacy and safety of levetiracetam and valproate in treatment of idiopathic generalized epilepsy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of juvenile myoclonic epilepsy or generalized tonic-clonic seizure alone
- •Regular monotherapy with levetiracetam or sodium valproate
排除标准
- •Poor drug adherence
- •Pregnancy
研究组 & 干预措施
Sodium valproate
Patients with idiopathic generalized epilepsy who were under treatment with valproate
干预措施: Sodium valproate (Drug)
Levetiracetam
Patients with idiopathic generalized epilepsy who were under treatment with levetiracetam
干预措施: Levetiracetam (Drug)
结局指标
主要结局
Seizure free rate
时间窗: 1 to 5 years
The percent of patients who remained seizure free on treatment
Time to first seizure
时间窗: 1 to 5 years
The interval between start of treatment and recurrence of seizure
次要结局
- Retention rate(1 to 5 years)
- Time to withdrawal(1 to 5 years)
研究者
Nasim Tabrizi
Associate professor of neurology
Mazandaran University of Medical Sciences
研究点 (1)
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