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临床试验/CTRI/2026/04/108811
CTRI/2026/04/108811尚未招募2 期

A comparative clinical study to assess the efficacy of aragwadhadi lepa and dhatryadi yoga in kitibha kushtha w.s.r to psoriasis

Sriganganagar College of Ayurvedic Science and Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年4月27日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1

研究概览

简要总结

Psoriasis is a chronic inflammatory, hyper proliferation skin disease that significantly affects patients quality of life. Psoriasis affects approximately 1.5- 3% of Caucasians but is less common in Asian, South American and African populations. It occurs equally in both genders and at any age; more than 50% of patients present before the age of 30 years. The age of onset follows a bimodal distribution, with an early-onset type in the teenage or early adult years, often with a family history of psoriasis. The later onset type is typically seen between 50 and 60 years, usually without a family history and with a less severe disease course. It affects approximately 2-3 % of the global population is characterized by a relapsing, remitting course. Despite the availability of various modern therapeutic modalities such as topical steroids, immunosuppressants, and biologics complete remission remains challenging, and long-term use is often associated with adverse effects, high cost, and the risk of relapse. Therefore, there is a growing interest in safer, affordable, and more sustainable therapeutic options. In Ayurveda, Kitibha Kushtha closely resembles the clinical features of psoriasis, including scaling, dryness, discoloration, and chronicity. Classical Ayurvedic texts emphasize both Bhahya Chikitsa (external therapy) and Abhyantara Chikitsa (internal therapy) in the management of Kushtha. In this study, an attempt will be made to provide patients with a safe, effective, and affordable form of preventive and curative management through the use of Aragwadhadi Lepa and Dhatryadi Yoga. Although both formulations are mentioned for skin disorders, comparative evidence based clinical studies evaluating their individual and combined efficacy in Kitibha Kushtha (psoriasis) are limited. Thus the study is necessary to bridge the gap between classical Ayurvedic knowledge and modern clinical evidence, contributing to the development of effective, holistic management strategies for psoriasis /Kitibha Kushtha.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Psoriatic lesions showing classical symptoms & signs of Kitibha Kushtha as described in Ayurvedic Samhitas as Shyava varna (dark/brownish discoloration), Kina sparsha (thickened skin), Khara sparsha (roughness), Parusham (hardness) Ugra Kandu (severe itching). 2.Patients having cardinal symptom of psoriasis like erythematous papules/plaques covered with dry brittle, Auspitz sign, Kobner phenomenon, Candle grease sign, silvery grayish white micaceaous scale etc. 3.Psoriatic lesions present on common sites such as elbows, knees, scalp or back, with disease duration generally less than
  • 10 years. 4.Participants capable of understanding the study and willing to provide informed consent.

排除标准

  • 1.Complicated cases of psoriasis like pustular psoriasis, psoriasis with arthritis or any other such type of complication.
  • 2.Patients having cardiac disease, renal disease and endocrine disorders were excluded from the study.
  • 3.Pregnant and lactating woman.
  • 4.Patients having any allergy history or sensitivity will be excluded from study.

研究者

发起方
Sriganganagar College of Ayurvedic Science and Hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Shilpa Verma

Sriganganagar College of Ayurvedic Science and Hospital

研究点 (1)

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