Use of Life History Calendars to Enhance Measurement of Lifetime Experience With Mental Disorders in Hong Kong.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,500
- 试验地点
- 2
- 主要终点
- Depression
研究概览
简要总结
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders.
To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study.
In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation.
This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All household members aged 25 years old and over are randomly sampled from the Census and Statistics Department List of Quarters
- •Live in the address sampled from the Census and Statistics Department List of Quarters
- •Reside in Hong Kong for at least six months in the past year
- •Able to read and communicate in Chinese or English
- •Without linguistic or cognitive difficulties
排除标准
- •Domestic workers
研究组 & 干预措施
CIDI-5
For the CIDI-5 group, respondents will directly partake in the CIDI-5 interview without responding to any inquiries regarding their life history.
干预措施: CIDI-5 (Diagnostic Test)
LHC-CIDI-5
For the LHC-CIDI-5 group, respondents, before initiating the CIDI-5, will begin with LHC, completing a calendar by answering questions about important personal experiences since birth until the interview year.
干预措施: LHC-CIDI-5 (Diagnostic Test)
结局指标
主要结局
Depression
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Major Depressive Episode (MDE) and Major Depressive Disorder (MDD)
Persistent Depression
时间窗: Immediately following intervention or recruitment
The main outcome in this module is the lifetime prevalence of Persistent Depressive Disorder (PDD)
Self Harm
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Suicidal Ideation, Suicidal Plan, Suicidal Attempt, Suicidal Gesture, and Nonsuicidal Self-Injury.
High Mood
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Manic Episode, Hypomanic, Bipolar I Disorder, Bipolar Sub Disorder, and Bipolar II Disorder
Worry and Anxiety
时间窗: Immediately following intervention or recruitment
The main outcome in this module is the lifetime prevalence of Generalized Anxiety Disorder (GAD)
Anger Attacks
时间窗: Immediately following intervention or recruitment
The main outcome in this module is the lifetime prevalence of Intermittent Explosive Disorder (IED)
Panic Attacks
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Panic Attack and Panic Disorder.
Obsessions and Compulsions
时间窗: Immediately following intervention or recruitment
The main outcome in this module is the lifetime prevalence of Obsessive-Compulsive Disorder (OCD)
Stressful Experiences
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Posttraumatic Stress Disorder (PTSD), PCL-SC PTSD, and PCL-5 PTSD.
Tobacco, Alcohol, and Drugs
时间窗: Immediately following intervention or recruitment
The main outcomes in this module are the lifetime prevalence of Alcohol Use Disorder (AUD) and Substance Use Disorder (SUD)
次要结局
未报告次要终点
研究者
Michael Y. Ni
Clinical Associate Professor
The University of Hong Kong