EUCTR2021-001019-95-IT进行中（未招募）1 期
Pharmacokinetic/pharmacodynamic aspects of colistin intravenous administration in critically ill patients suffering from hospital infections caused by multi-antibiotic-resistant germs and receiving continuous renal replacement therapy. - COLIMICINA
FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE0 个研究点目标入组 20 人开始时间: 2021年6月8日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •oAge> 18 yy
- •oDuration of treatment planned for at least 48 hours
- •oInfection where the involvement of MDR germs is documented or highly probable
- •oContinuous renal replacement therapy
- •oAcute renal failure, stage III of the 2012 KDIGO classification
- •oHalf-life of the continuous renal replacement therapy filter less than 48 hours.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 5
排除标准
- •oState of pregnancy
- •oRefusal of informed consent
- •oKnown hypersensitivity to polymyxins
- •oClinical condition with high probability of death, according to Symplified Acute Physiology Score (SAPS II)
- •oPartial maintenance of renal function, defined by stages I and II of the 2012 KDIGO classification.
- •oRenal replacement therapy filter other than AN69 ST 150
研究者
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