Effect of photo-biomodulation on Implant stability, Bone density and Bio-chemical markers in dental implants- A randomized controlled clinical trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Implant stability
研究概览
简要总结
The aim of this current study is to evaluate the effect of photobiomodulation using 980nm diode laser on implant stability, bone density and bio-chemical markers levels(OPG and RANKL)around dental implants.The total sample size is 22 patients.These patients will be divided in to two groups randomly. Group-A (control) includes 22 patients in which implants will be placed in a conventional approach.Group-B(test)includes 22 patients in which implants will be placed in a conventional approach and laser irradiation using 980nm diode laser with 6J energy/session, time of 60sec, power of 0.1W in a continuous, non-contact mode in a sweeping motion will be done immediately after osteotomy site preparation on bone, after suturing on soft tissue and after suture removal on the 7th day.The parameters being measured in both the groups are implant stability at baseline and 3 months using resonance frequency analyzer, bone density and crestal bone levels at baseline and 6 months using CBCT, bio-marker levels in PICF at 3.5 months and 6 months using ELISA kits and healing of soft tissues 1 week post-surgically using Hamzani and chaushu’s healing index.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1 Mandibular posterior edentulous areas 2 Age group of 20-60 years.
- •3 Adequate depth and width of bone should be present.
排除标准
- •1 Patients with uncontrolled systemic diseases. 2 Pregnancy or lactating women. 3 Patients under anticoagulant therapy. 4 Chronic smokers. 5 Patients with infectious diseases ( HIV, Hepatitis.
- •B,C etc ) 6 Patients under antibiotic therapy. 7 Patients undergoing radiation therapy. 8 Patients undergoing bis-phosphonate therapy.
结局指标
主要结局
Implant stability
时间窗: Implant stability at baseline and 3 months
次要结局
- 1 Bone density(2 Bio-marker levels( OPG and RANKL))
研究者
Dr Lakamsani Kavya Sri
Vishnu dental college
