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临床试验/PACTR202109625368648
PACTR202109625368648招募中未知

Efficacy of intraarticular combined injection of platelet-rich plasma and botulinum toxin versus platelet-rich plasma monotherapy for knee osteoarthritis: A randomized superiority trial

Mansoura university hospital0 个研究点目标入组 60 人开始时间: 2021年9月8日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
45 Year(s) 至 64 Year(s)(—)
性别
All

入选标准

  • Age of 40–70 years old
  • Suffering from knee pain in the past six months
  • History of complaints for at least one month
  • The need for painkillers
  • Knee osteoarthritis was confirmed by radiography (Kellgren-Lawrence classification grade 2–3).

排除标准

  • presence of systemic disorders (ie, diabetes mellitus, immunodeficiency, and collagen vascular diseases)
  • the history of malignancy, the
  • history of autoimmune diseases or platelet disorders,
  • body mass index of over 33 kg/m2,
  • the presence of IAIs within the past three months before the injection,
  • the history of a recently occurred severe knee trauma, knee septic arthritis, the active ulcer or septic arthritis of the knee, genu varum or valgum of over 20°,
  • history of clinically significant cardiac, hepatic, renal, or neurological dysfunction,
  • coagulopathy,
  • known allergy to study drugs

研究者

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