DRKS00003551招募中4 期
graft function adapted tacrolimus therapy after liver transplantation (GRAFTT) - GRAFTT
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 210
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Inclusion criteria
- •-Patients intended for orthotopic deceased-
- •- Recipient age =18 yrs.
- •- Capability to understand the purpose and
- •the risk of the study
- •- Written informed consent prior LT
排除标准
- •- Participation in other clinical trials during <28 days before LT
- •- any organ transplantation before enrollment, High-urgent transplantation, split liver LT, living donor LT, combined multi-organ transplantation, AB0 incompatible grafts, retransplantation
- •- Recipients with malignant tumors beside HCC respecting the Milan criteria or liver metastasis
- •-Target trough levels of tacrolimus differing from 10-15 ng/mL in the first 14 days after LTx)
- •- planned use of other immunosuppressive drugs including ciclosporine A, sirolimus, everolimus, azathioprine in the first 14 days after LTx
- •- patients with known intolerance of tacrolimus
- •- patients with a history of substance or drug abuse
- •- patients with psychiatric disorders or any forms of substance abuse not capable of understanding the purpose and risks of the study
- •- subjects known to be HIV positive- pregnant woman or breastfeeding mother
研究者
相似试验
招募中
2 期
Effect of tacrolimus for patients with refractory Crohn's disease: A randomized, placebo-controlled trial.s diseaseCrohn's diseaseJPRN-UMIN000002796Department of Gastroenterology and Hepatology, Kyoto University50
已完成
不适用
Efficacy and Safety of Tacrolimus as Secondline Therapy for Patients With Autoimmune Hepatitis Pilot StudyAutoimmune HepatitisJPRN-UMIN000030743Hiroshima University Hospital5
已完成
不适用
The effect of proactive therapy with tacrolimus and betamethasone butyrate on atopic dermatitis: Randomized placebo-controlled studyatopic dermatitisJPRN-UMIN000006955Dept of dermatology, Osaka university90
招募中
不适用
Management of the combination of tacrolimus with azoles: effect of tacrolimus formulation on drug-drug interaction magnitudeMycoses due to opportunistic pathogensfungal infection in patients with immune deficiencies who would otherwise not be infected10017528NL-OMON54925niversitair Medisch Centrum Groningen24
已完成
不适用
Combination therapy of tacrolimus and intravenous cyclophosphamide for remission induction of lupus nephritislupus nephritisJPRN-UMIN000004893Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University16