Feasibility of Measurement of High Order Aberrations in Late Stages Keratoconus by Using an Adaptive Optics Visual Simulator AOVIS-I
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- The primary outcome of the study is to evaluate the AOVIS-I and its wave-front sensor with high dynamic range for measuring high-order aberrations in patients with late stages (3 and 4) of keratoconus
研究概览
简要总结
The instrument that will be used in the study is the Murcia monocular Adaptive Optics Visual simulator (AOVIS-I). The system provides an objective characterization of the optical quality of the patient's eye by application of wave-front sensing technology. The optical condition of every eye is represented by its wave aberration. This characterization overcomes the current description based only in refractive errors. This provides an accurate description of the optics of the eye based on the assessment of the whole set of ocular aberrations. The particular wave-front sensor is of a Hartmann-Shack type. One characteristics of this wave-front sensor is its high dynamic range allowing measuring highly aberrated eyes, such as patients with keratoconus.
详细描述
The complete procedure in one patient takes less than 5 minutes and is completely non-invasive.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •to be able to understand an information and give a consent
- •patients over 18
- •patients with keratoconus
- •affiliated to medical insurance.
排除标准
- •non keratoconus patients
- •patients under 18
- •pregnant women or nursing mothers
- •ocular surgery 90 days before inclusion
- •ocular infection
- •keratitis
- •restless patients
结局指标
主要结局
The primary outcome of the study is to evaluate the AOVIS-I and its wave-front sensor with high dynamic range for measuring high-order aberrations in patients with late stages (3 and 4) of keratoconus
时间窗: at the 1st day
次要结局
- To evaluate the reliability of the measures in early stages (1 and 2) of keratoconus as compared with a "classic aberrometer".(at the 1st day)
- To describe the measures obtained in advanced stages (3 and 4) of keratoconus.(at the 1st day)