NL-OMON39088已完成不适用
The influence of time of administration on tamoxifen pharmacokinetics. - Different times of tamoxifen administration.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •-Histological or cytological confirmed diagnosis of breast cancer, for which treatment with tamoxifen is indicated (to be evaluated by the treating physician);
- •-Use of tamoxifen for at least 4 weeks and willing to continue the treatment until the end of the study;
- •-Age > 18 years;
- •-WHO performance <= 1;
- •-Written informed consent;
- •-Adequate renal and hepatic functions (see protocol);
- •-Adequate hematological blood counts (see protocol);
- •-No chemotherapy within the last 4 weeks before start;
- •-No radiotherapy within the last 4 weeks before start.
排除标准
- •-Pregnant or lactating patients;
- •-Serious illness or medical unstable condition requiring treatment, symptomatic CNS metastases or history of psychiatric disorder that would prohibit the understanding and giving of informed consent;
- •-More than one tamoxifen dose per day (20 or 40 mg);
- •-Non-compliance.
研究者
相似试验
已完成
2 期
Evaluation of the effects of increasing tamoxifen dose on the treatment process in breast cancer patientsBreast cancer.Malignant neoplasm of breastIRCT2015082323734N1Isfahan University of Medical Siences100
招募中
不适用
The TOTAM studyAdjuvante behandeling van oestrogeenreceptor positieve (HR+) borstkanker.NL-OMON23682Erasmus Medical Center, Rotterdam
进行中（未招募）
1 期
Therapeutic Drug Monitoring guided tamoxifen dosing: a feasibility study in patients with hormone positive breast cancerHormone positive breast cancerEUCTR2017-005124-24-NLErasmus MC Cancer Institute400
已完成
不适用
Therapeutic Drug Monitoring guided tamoxifen dosing: a feasibility study in patients with hormone positive breast cancerHormone positive breast cancer10006291NL-OMON52690Interne Oncologie457
尚未招募
4 期
The effect of rate of administration of tramadol on incidence of post operative nausea and vomiting after any surgical operation for which significant postoperative pain is expectedACTRN12606000201572ANZCA (australaian and New Zealand College of Anaesthetists)150