ISRCTN31503555已完成未知
Oral topical cyclo-oxygenase 2 inhibitors (COX2-1) mouthwash for the treatment of oral dysplasia: a pilot non-randomised interventional proof of concept study
Coventry University Hospital (UK)0 个研究点目标入组 13 人开始时间: 2010年4月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 13
研究概览
简要总结
2012 Results article in http://www.ncbi.nlm.nih.gov/pubmed/22731119 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients with clinically evident leukoplakia
- •2. Can attend follow up
- •3. Requiring biopsy and surgery
- •4. 18 years old or over, either sex
- •5. Able to give informed consent
- •6. Not known to be pregnant
排除标准
- •1. Histologically confirmed cancer
- •2. Prior oral cancer
- •3. Patients on aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroid treatment
- •4. Current treatment of oral dysplasia with topical/systemic treatment
- •5. Active peptic ulcer disease
- •6. History of aspirin induced asthma, stomach ulcers or aspirin sensitivity
- •7. History of associated angioedema, urticaria or suspected aspirin allergy in the past
研究者
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