Oculomotor Function Testing in Patients Who Suffered Concussions
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- self-paced saccade
研究概览
简要总结
This is a prospective longitudinal study which aims to compare oculomotor function and visual scanning behaviour (VSB) of participants who suffered concussion with healthy controls with no concussion. This study also aims to investigate the pattern of change in oculomotor function and visual scanning behaviour (VSB) in the participants over a 6-month period.
详细描述
Primary Objective
- To identify differences in oculomotor function and visual scanning behaviour (VSB) between participant with and without acute concussion
- To investigate patterns of change and recovery in oculomotor function and VSB in participants who suffered a concussion
Secondary Objective
• To investigate the association between the oculomotor function and concussion-related symptoms
This is a prospective longitudinal study which aims to evaluate differences in oculomotor function and visual scanning behaviour (VSB) between participants who suffered acute concussion and healthy controls with no concussion. This study also aims to investigate the pattern of change in oculomotor function and visual scanning behaviour (VSB) in the participants over a 6-month period.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants (age group 18-60) who present to the emergency department in the University Health Network within 7 days of concussion
排除标准
- •Age less than 18
- •Any other neurological disorder (e.g. seizures)
- •Any systemic illness known to affect the brain (e.g. diabetes and lupus)
- •History of major psychiatric disorder (e.g. bipolar, schizophrenia)
- •History of known developmental disorders (e.g. attention deficit disorder, dyslexia)
- •Any lesion detected by MRI prior to the study
- •Any previous vision disorder that prevents the participant from performing the self-paced saccade task
- •Any brain injury more severe than concussion
- •Participants (age group 18-60) with no previous history of concussions who are age, education and sex-matched to the patients' group will be recruited from the community.
- •Healthy Controls:
- •Inclusion Criteria:
- •Participants (age group 18-60) with no previous history of concussions who are age, education and sex-matched to the patients' group will be recruited from the community.
- •Exclusion Criteria:
- •All exclusion criteria mentioned above for patients plus any history of concussions
结局指标
主要结局
self-paced saccade
时间窗: 2 years
Number of self paced saccadic eye movements in 60 seconds
次要结局
未报告次要终点
研究者
Carmela Tartaglia
Marion and Gerald Soloway Chair in Brain Injury and Concussion Research Associate Professor, University of Toronto
University Health Network, Toronto