NCT01837056已完成不适用
Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis
National Institute of Health, Korea0 个研究点目标入组 98 人开始时间: 2011年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 98
- 主要终点
- Number of patients with positive result for serum antibody to Toxoplasma gondii and Toxocara canis
研究概览
简要总结
Investigate the prevalence of Toxoplasma gondii and Toxocara canis in Uveitis
- serum antibody to T. gondii and T. canis
- PCR with peripheral blood for T. gondii and T. canis
- PCR with aqueous humor for T. gondii and T. canis
- Clinical manifestation of patient with uveitis
详细描述
Consecutive patients with uveitis are enrolled in Nune Eye Hospital.
Serum ELISA
- IgM,IgG antibody to Toxoplasma gondii
- IgG antibody to Toxocara canis
PCR
- PCR with serum and aqueous humor to Toxoplasma gondii
- PCR with serum and aqueous humor to Toxocara canis Clinical characteristics
- visual acuity
- intraocular pressure (IOP)
- location and degree of inflammation
- other fundus findings were recorded
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with uveitis
排除标准
- •Patients with history of major ophthalmic surgery within 6 months
- •antiviral, antifungal or antiparasitic therapy within 6 months
结局指标
主要结局
Number of patients with positive result for serum antibody to Toxoplasma gondii and Toxocara canis
时间窗: at baseline
proportion of patients with seropositive for Toxoplasma gondii and Toxocara canis among patients
次要结局
- Number of patients with positive PCR with peripheral blood and aqueous humor to Toxoplasma gondii and Toxocara canis(at baseline)
研究者
Lim, Su Jin
The retina staff
Nune Eye Hospital, Seoul, Korea
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