Treatment of Complex Regional Pain Syndrome, a Qualitative Interview Study and a Case Series With Long-term Follow-up
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Diagnosis
研究概览
简要总结
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features. The diagnosis is subdivided in CRPS type 1 where no nerve injury has been identified, and CRPS type 2 when a major nerve injury has been verified.
A combination of exposure in vivo, a form of behaviour therapy where the patient is gradually confronted with avoided movements and activities, and interventions directly targeting a hypothesized cortical reorganisation is an interesting novel approach for treating CRPS.
The present study consists of (1) a qualitative interview study with 10-15 subjects that has received this form of treatment, in order to better understand their experience and effects of the treatment, and (2) a case series with long-term follow-up of 3-5 subjects that received the treatment för 5-8 years ago, in order to study the long term effects of the treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Has participated in multimodal treatment for CRPS at Uppsala University Hospital
排除标准
- •Other serious physical or mental condition
结局指标
主要结局
Diagnosis
时间窗: 1 day
Whether the subject still fulfill diagnostic criteria for CRPS
Subjective experience
时间窗: 1 day
A qualitative interview targeting the subjects own experience of the treatment and its effect
次要结局
- Acceptance of pain(1 day (0-156, higher scores mean a better outcome))
- Level of pain(1 day)
- Fear of pain(1 day (0-52, lower scores mean a better outcome))
- Subjective experience of quality of life 3(1 day)
- Neglect of the affected limb(1 day (0-36, lower scores mean a better outcome))
- Subjective experience of quality of life(1 day)
- Global impression of change(1 day)
- Pain catastrophizing(1 day (0-52, lower scores mean a better outcome))
- Subjective experience of quality of life 2(1 day)
- Avoidance of activities(1 day (0-100, lower scores mean a better outcome))