NCT00619086已完成不适用
Does a Single Dose of Steroid Before Thyroidectomy Improve Postoperative Nausea, Pain and Vocal Function?
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Nausea
研究概览
简要总结
We evaluated the effects of giving a single dose of steroid before thyroid surgery in a single institutional, double-blinded, randomized controlled trial. Postoperative nausea, pain, and vocal function were significantly improved after steroid administration compared to controls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing thyroid surgery for benign disease
排除标准
- •Depression
- •Chronic pain disorder
- •Insulin dependent diabetes mellitus
- •History of PONV
- •Pregnancy
- •Age < 18 years
- •Received antiemetic therapy within 48 hours
研究组 & 干预措施
A, 1
Placebo Comparator
Placebo 45 minutes prior to surgery
干预措施: Placebo (Drug)
A, 2
Active Comparator
8 mg Dexamethasone 45 minutes prior to surgery
干预措施: Dexamethason Helvepharm ® (Drug)
结局指标
主要结局
Nausea
时间窗: 0-72 hours postoperative
次要结局
- Pain, vocal function(0-72 hours postoperative)
研究者
研究点 (1)
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