A Comparison of Transversus Abdominis Plane Blocks Versus Continuous Intravenous Lidocaine for Kidney Transplant Surgery
试验速览
- 阶段
- 2 期
- 入组人数
- 124
- 试验地点
- 1
- 主要终点
- Opioid Consumption
研究概览
简要总结
This study will compare continuous intravenous lidocaine against single-injection transversus abdominis plane (TAP) block as a modality for postoperative analgesia in kidney transplant surgery.
详细描述
This study is a non-inferiority trial designed to assess the analgesic efficacy of an intravenous (IV) lidocaine infusion against single-injection transversus abdominis plane (TAP) block in patients undergoing kidney transplant surgery. The investigators propose a study of 124 subjects randomized into two groups. The control group will receive a TAP block. The study group will receive a continuous IV lidocaine infusion. The investigators hypothesize that there will be no statistically significant difference in postoperative opioid consumption between the two groups in the first 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Kidney transplant recipient
- •>18 years old
- •Consent to participate
排除标准
- •<18 years old
- •Refusal to participate
- •Chronic opioid use
- •Seizure disorder
- •Allergy to local anesthestics
- •Severe hepatic disease
研究组 & 干预措施
TAP Block
Single-injection transversus abdominis plane block
干预措施: Transversus Abdominis Plane Block (Procedure)
IV Lidocaine
Continuous intravenous lidocaine infusion
干预措施: Intravenous Lidocaine (Drug)
结局指标
主要结局
Opioid Consumption
时间窗: 0-24 Hours
Total opioid utilization
次要结局
- Pain Scores(0-48 Hours)
- Opioid Consumption(24-48 Hours)
- Opioid-Related Adverse Events(0-48 Hours)
- Block/Infusion-Related Adverse Events(0-48 Hours)
- Opioid Usage(30 days from discharge)
研究者
Neil Hanson
Anesthesiologist
Benaroya Research Institute