Quantification and Characterization of Circulating Tumor Cells in Solid Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 206
- 试验地点
- 1
- 主要终点
- Documentation of the Quality of CTCs from Patients with Solid Tumors
研究概览
简要总结
The purpose of this study is to identify circulating tumor cells in patients with solid tumors. Quantify and characterize these cells, collect patient information in regards to the patient's cancer. Develop a database and a sample repository where future analysis could be done.
详细描述
The primary purpose of this correlative study is to create a prospective database documenting the quantity and characterization of circulating tumor cells (CTCs) in solid tumor patients as identified by a various laboratory techniques and analyses. The investigators are developing this resource to provide data to achieve the following objectives: 1) correlate CTCs with known prognostic factors, 2) correlate CTCs with burden of disease, 3) evaluate the ability of CTCs to be used in the surveillance of disease recurrence, and 4) evaluate CTCs ability to be used as a biomarker for treatment response.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years of age
- •Biopsy proven solid tumor malignancy
- •Seen at UNC Chapel Hill Hospital and Health Care System
- •Consents to abstraction of their medical records
- •Signed an institutional review board (IRB)-approved informed consent document for this protocol
排除标准
- •< 18 years of age
- •Dementia, altered mental status, incarceration or any psychiatric condition that would prohibit the understanding or rendering of informed consent.
结局指标
主要结局
Documentation of the Quality of CTCs from Patients with Solid Tumors
时间窗: Through study completion, an average of 5 years
Enumeration of participants' circulating solid tumor cells
Documentation of the Characterization of CTCs from Patients with Solid Tumors
时间窗: Through study completion, an average of 5 years
Characterization of participants' circulating solid tumor cells
次要结局
未报告次要终点