NCT00380263已完成不适用
Basic Scientific Research Investigating PACAP38 Headache Inducing Effects in Migraine Patients
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
研究概览
简要总结
To investigate headache score and accompanying symptoms during and after infusion of PACAP38 i migraine patients
详细描述
To investigate headache score and accompanying symptoms during and after infusion of PACAP38
Changes in regional cerebral blood flow (rCBF) in the area supplied by middle cerebral artery (MCA), blood flow in MCA, diameter of the superficial temporal artery (STA) and radial artery (RA)
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy migraine patient without aura
- •Aged 18-50
- •50-100 kg
- •Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical sterilisation and long lasting gestagen.
排除标准
- •Tension type headache more than five times/month
- •Other primary headaches
- •Daily medication except contraceptives
- •Drug taken within 4 times the halflife for the specific drug except contraceptives
- •Pregnant or lactating women
- •Exposure to radiation within the last year
- •Headache within the last 48 hours before start of trial
- •Hypertension
- •Hypotension
- •Respiratory or cardiac disease
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
PACAP38 Induced Headache, Migraine and Flushing in Patients With MigraineMigraine Without AuraNCT03881644Danish Headache Center37
已完成
不适用
PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With RosaceaRosaceaNCT03878784Danish Headache Center38
Unknown
不适用
PACAP-38 Infusion in Patients With Cluster HeadacheCluster HeadacheNCT03814226Danish Headache Center45
Unknown
不适用
Hypersensitivity to PACAP-38 in Post-Traumatic HeadachePost-Traumatic HeadacheNCT05378061Danish Headache Center21
已完成
不适用
Effect of PACAP38/VIP on Migraineurs Measured by Magnetic ResonanceMigraine Without AuraNCT01471990Glostrup University Hospital, Copenhagen24