NCT07604610招募中不适用
Epicardial Fat Tissue Assessed by Echocardiography in Russian and Asian Populations: Association With Chronic Non-Communicable Diseases and Risk Factors
National Medical Research Center for Therapy and Preventive Medicine1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2026年5月4日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
研究概览
简要总结
Visceral obesity is a well-established risk factor for the development of chronic non-communicable diseases (NCDs). Epicardial fat tissue (EFT) is located on the surface of the myocardium and may directly affect cardiac function and contribute to structural and functional remodeling.
According to the literature, increased EFT thickness is associated with a wide range of NCDs, disease severity, and prognosis.
The aim of this study is to investigate the associations between EFT thickness and clinical and anamnestic parameters, as well as to evaluate the prognostic value of this parameter in patients aged 50-70 years from the Russian Federation, Kazakhstan, Uzbekistan, and Kyrgyzstan.
详细描述
The study is designed to:
- Assess physical examination findings, laboratory parameters, and comorbidities;
- Evaluate transthoracic echocardiography parameters;
- Analyze associations between EFT thickness and clinical and anamnestic characteristics;
- Determine threshold values of EFT thickness associated with structural and functional myocardial remodeling;
- Conduct follow-up via telephone to assess study endpoints;
- Evaluate the prognostic value of EFT thickness with respect to a composite endpoint.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 50-70 years undergoing transthoracic echocardiography in inpatient or outpatient settings;
- •Ability and willingness to provide informed consent.
排除标准
- •Refusal to sign informed consent;
- •Inability to perform transthoracic echocardiography or poor image quality;
- •Severe psychiatric disorders.
研究者
研究点 (1)
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