The African Critical Illness Outcomes Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20,159
- 试验地点
- 1
- 主要终点
- Presence of critical illness
研究概览
简要总结
In Africa, the prevalence of critical illness is likely to be higher due to a greater burden of disease, and the associated mortality higher due to limited resources. This is a prospective, observational study to rapidly establish the prevalence of critical illness in in-hospital adult patients in Africa, and the resources available to provide essential critical care (care that should be available to every patient in the world) and factors associated with mortality. Rapid dissemination of these findings may help mitigate mortality from critical illness in Africa. These points provide the rationale for the African Critical Illness Outcomes Study.
详细描述
STUDY OBJECTIVES
The objectives of this study are to determine:
- The proportion of hospital patients who are critically ill,
- The mortality associated with critical illness,
- The proportion of critically ill patients who receive essential emergency and critical care,
- The relationship between essential emergency and critical care provision, and mortality, and
- The availability of resources necessary to provide essential emergency and critical care.
STUDY DESIGN
An African multi-centre prospective observational cohort study of adult (≥18 years) in-hospital patients. Patient follow up will be for a maximum of 7 days in-hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult patients aged 18 years or over who have been admitted for inpatient care in any department or ward in participating hospitals.
排除标准
- 未提供
结局指标
主要结局
Presence of critical illness
时间窗: 7 days
The number of participants with critical illness.
In-hospital mortality (censored at 7-days)
时间窗: 7 days
The number of participants with in-hospital mortality (censored at 7-days)
次要结局
- Provision of essential emergency and critical care(7 days)
- Length of hospital stay(7 days)
- Number of essential emergency and critical care resources available for care(7 days)
研究者
Bruce Biccard
Co-chief Investigator
University of Cape Town