NCT01050725暂停不适用
Investigating Proteomic Biomarkers of Radiation Therapy Outcome: A Pilot Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 100
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to determine whether specific assays of DNA damage repair proteins can be used in patients undergoing radiation therapy. The ultimate goal of this research is to develop clinically useful biomarkers from blood samples that could be used to customize radiation treatment for individuals, leading to reduced side effects and improved outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients > 18 years of age with primary lung, esophageal or rectal cancer receiving neo-adjuvant chemoradiotherapy before planned resection
- •patients with clinically localized prostate cancer receiving definitive radiation therapy with external beam treatment. brachytherapy as a boost and/or hormonal therapy are allowed.
- •patients with head and neck, lung, esophageal or cervical cancer who will receive definitive radiotherapy
排除标准
- •prior history of chemotherapy given within 6 months before enrollment.
- •prior radiotherapy or radionuclide treatment and/or brachytherapy within 6 months prior to enrollment.
- •unwillingness to comply with tests, protocol, or informed consent.
- •concurrent enrollment on any protocol that would require non-compliance with treatment procedures.
- •chemotherapy required within 2 hours following first dose of XRT.
- •PET scan done within 48 hours of first blood draw.
- •nuclear medicine exposure within 4 days prior to first draw.
研究者
研究点 (1)
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