A Multicenter, Prospective, Real World Observational Study for Chronic Total Occlusion
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 4,006
- 试验地点
- 19
- 主要终点
- Composite event of all cause death, myocardial infarction, stroke or all kinds of repeat revascularization
研究概览
简要总结
This study evaluated the long-term outcome of patients with chronic total occlusion treated with percutaneous coronary intervention, medical treatment or coronary artery bypass grafting.
详细描述
This study is connected with Decision-CTO trial(NCT01078051). Randomized subjects and registry group subjects from Decision-CTO trial continue 10 years follow-up on this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with angina or silent ischemia and documented ischemia
- •Patients with De novo chronic coronary occlusion ≥ 3months and reference diameter ≥ 2.5 mm on coronary angiography
- •Age > 18 years
排除标准
- •Refuse to participate in this study
研究组 & 干预措施
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
干预措施: Percutaneous coronary intervention (Procedure)
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
干预措施: Coronary Artery Bypass Grafting (Procedure)
Chronic coronary occlusion patients
≥3 months chronic total occlusion on coronary angiography
干预措施: Medical treatment (Drug)
结局指标
主要结局
Composite event of all cause death, myocardial infarction, stroke or all kinds of repeat revascularization
时间窗: 10 years
次要结局
- Event rate of all cause death(10 years)
- Event rate of rehospitalization due to acute coronary syndrome(10 years)
- Event rate of acute myocardial infarction(10 years)
- Event rate of stroke(10 years)
- Event rate of Procedural success(5 days)
- Event rate of repeat revascularization(10 years)
- The rate change of left ventricular ejection fraction(10 years)
- Composite event of death, myocardial, stroke or repeat revascularization(10 years)
研究者
Seung-Jung Park
Professor,University of Ulsan College of Medicine
Asan Medical Center