NL-OMON53667招募中不适用
A multicenter prospective cohort study comparing random biopsies with Wide-Area Transepithelial brush-Sampling (WATS) for surveillance of Barrett*s esophagus.;The WATS-EURO2 study - The WATS-EURO2 study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 239
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Patients age: >= 18 years
- •- BE with a circumferential extent of >=2cm and a total maximum extent of <=18cm
- •(in case of prior ER: BE length is measured after ER). Or a circumferential
- •extent of 0-1 cm with a maximum extent of >=4cm.
- •- Cohort 1: Patients referred for work-up of IND, LGD, HGD or low-risk cancer
- •(m1 to sm1, without lympho-vascular invasion and poor differentiation), either
- •diagnosed in random biopsies or in prior endoscopic resection specimen within
- •18 months prior to baseline endoscopy
- •- Cohort 2: Patients with known BE without a diagnosis of dysplasia in the last
- •18 months, enrolled in endoscopic surveillance programs
- •- Ability to give written, informed consent and understand the responsibilities
- •of participation
排除标准
- •- Patients with visible lesions according to the Paris classification at the
- •time of the WATS and random biopsy testing (prior endoscopic resection is
- •- Patients with high-risk cancer after endoscopic resection: either sm2/3
- •invasion, poor differentiation, lympho-vascular invasion, or R1 vertical
- •resection margin
- •- Patients within six weeks after endoscopy with biopsies and/or ER
- •- History of esophageal or gastric surgery other than Nissen fundoplication
- •- History of esophageal ablation therapy
- •- Presence of esophageal varices
- •- Subject has a known history of unresolved drug or alcohol dependency that
- •would limit ability to comprehend or follow instructions related to informed
- •consent, post-treatment instructions, or follow-up guidelines
研究者
相似试验
尚未招募
不适用
Comparison of administrative methods of terlipressin for esophageal variceal bleedingDiseases of the digestive systemKCT0006107Korea University Ansan Hospital126
招募中
不适用
A prospective randomized multi-center study comparing endoscopic pneumodilation and per oral endoscopic myotomy (POEM) as treatment of idiopathic achalasiadysfagieidiopatic achalasiesphincter into the esophagus10018008NL-OMON53016niversity Hospital Leuven40
进行中（未招募）
不适用
A trial in which will be studied if the addition of a medicine that is used for improving platelet counts (eltrombopag) to the regular treatment for aplastic anemia (hATG + CsA) also improves the numbers of other cell lines and therefore the overall bone marrow function.Idiopathic (Severe) Aplastic Anemia, a bone marrow failure syndrome which results in the normal hematopoietic tissue completely missing from the bone marrow, accounting for the subsequent pancytopenia.MedDRA version: 18.0Level: PTClassification code 10002967Term: Aplastic anaemiaSystem Organ Class: 10005329 - Blood and lymphatic system disordersEUCTR2014-000363-40-ESEuropean Society for Blood and Marrow Transplantation200
进行中（未招募）
1 期
A trial in which will be studied if the addition of a medicine that is used for improving platelet counts (eltrombopag) to the regular treatment for aplastic anemia (hATG + CsA) also improves the numbers of other cell lines and therefore the overall bone marrow function.Idiopathic (Severe) Aplastic Anemia, a bone marrow failure syndrome which results in the normal hematopoietic tissue completely missing from the bone marrow, accounting for the subsequent pancytopenia.MedDRA version: 19.0Level: PTClassification code 10002967Term: Aplastic anaemiaSystem Organ Class: 10005329 - Blood and lymphatic system disordersEUCTR2014-000363-40-NLEuropean Society for Blood and Marrow Transplantation200
已完成
3 期
A prospective Randomized multicenter study comparing horse Antithymocyte globuline (hATG) + Cyclosporine A (CsA) with or without Eltrombopag as front-line therapy for severe aplastic anemia patients.10018849panmyelopathybonemarrow failureNL-OMON44180European society for Blood and Marrow Transplantation48