NCT02341365已完成不适用
Impact of Vitamin D Levels on Ovarian Reserve and Ovarian Response to Controlled Stimulation in Egg Donors
IVI Madrid0 个研究点目标入组 269 人开始时间: 2013年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 269
- 主要终点
- Numbers of oocytes retrieved
研究概览
简要总结
Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.
详细描述
Design: Retrospective study. Setting: University affiliated private IVF center. Intervention: Serum analysis of vitamin D, bioavailable vitamin D, antimullerian hormone (AMH), antral follicular count (AFC), reproductive outcome of oocytes recipients Main outcome measure: AMH, AFC, number of oocytes retrieved and number of mature oocytes, pregnancy and implantation rate of donated oocytes'recipients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 34 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Caucasian race,
- •between 18 and 34 years of age,
- •all donors had normal menstrual cycles of 26-34 days,
- •normal weight range (BMI 18- 25 Kg/m2),
- •normal uterus and ovaries on transvaginal ultrasound (no signs of polycystic ovarian syndrome), and
- •an antral follicle count (AFC) >10,
- •normal karyotype
排除标准
- •current or past exposure to radiation or hazardous chemical substances,
- •history of drug use,
- •family history of hereditary chromosomal diseases,
- •sexually transmitted diseases
结局指标
主要结局
Numbers of oocytes retrieved
时间窗: 2 months
次要结局
- AMH(2 months)
- implantation rate(2 months)
- pregnancy rate(2 months)
- AFC(2 months)
- number of mature oocytes(2 months)
研究者
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