ISRCTN38196008已完成未知
A pilot study regarding regional anticoagulation by a citrate containing dialysis fluid
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Hemodialysis patients
- •2. Older than 18 years
- •3. Cardiovascular stable during and after their hemodialysis sessions
- •4. Taking acenocoumarol, fenprocoumon, acetylsalicylic acid, dipyridamol, clopidogrel, prasugrel or a combination here of
- •5. Good functioning arteriovenous shunt or fistula (blood flow >450 ml/min) for dialysing with two needles or double lumen hemodialysis catheter (blood flow >250ml/min)
排除标准
- •1. Unable to give informed consent
- •2. Unstable during hemodialysis i.e. Drop of blood pressure, muscular cramps
- •3. With an increased risk of being unstable during hemodialysis
- •4. With predialysis an ionized calcium <1.0 mmol/l
- •5. With changes in their dialysis protocol during the study i.e. Change of type and/or size of dialyzer, or change in blood- and/or dialysis fluid flow or change of dialysis modality (hemodialysis, hemofiltration, hemodiafiltration) or change in ultrafiltration
- •6. With a decrease in Hb >0.5 mmol/l during the study
- •7. With an increase of erythropoietin dosage >25% during the study
- •8. With a dysfunctioning arteriovenous shunt or fistula or hemodialysis catheter (see inclusion criteria)
- •9. With a coagulation defect not to be attributed to the used medication
研究者
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