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临床试验/NCT00216853
NCT00216853已完成不适用

A Study of Vaginal MicroFlora and Immune Profiles of Patients With Recurrent Urinary Tract Infection

Lawson Health Research Institute1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2003年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
44
试验地点
1

研究概览

简要总结

The purpose of this study is to determine the extent to which vaginal microflora and immune profiles of patients with urinary tract infection (UTI) differ from healthy controls.

详细描述

Recurrent urinary tract infections, which occur mostly in the female population, can be potentially harmful if not treated and significantly reduce quality of life. By characterizing the vaginal microflora and immune profiles of women that suffer recurrent UTIs in contrast to a healthy age matched normal group of women (with no history of recurrent UTIs), we can better understand the differences. This in turn can lead to development of better quality probiotics that will be based on their scientific basis, clinical efficacy, and quality in terms of shelf life and delivery to target sites. The reduction in only one third of UTI cases seen each year would have a significant impact on reducing health care costs.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Inclusion Criteria for UTI Group:
  • At least 2 recurrent UTIs within the last year
  • Written informed consent
  • Inclusion Criteria for Normal Group:
  • No UTI within the past 5 years
  • Written informed consent

排除标准

  • Exclusion Criteria for Both Groups:
  • Urinary tract anomalies
  • Evidence of a neurogenic bladder
  • Known immunodeficiencies
  • Use of antibiotics, within the last month
  • Concomitant use of oral steroids
  • Known renal calculi
  • Previous or ongoing chemotherapy

研究者

申办方类型
Other

研究点 (1)

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