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临床试验/NCT02435017
NCT02435017已完成不适用

Nutrition Risk Screening in Chronic Kidney Disease (CKD) From the National Health and Nutrition Examination Survey

Linda W. Moore0 个研究点目标入组 7,895 人开始时间: 2003年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
7,895
主要终点
Serum phosphorus concentration

研究概览

简要总结

Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function. Substudies will be performed to review the association of nutrients and overall dietary intake compared to biomarkers available in NHANES during this period.

详细描述

Data from NHANES 2003-2006 were used to evaluate the relationship between estimated dietary phosphorus intake and the measured serum phosphorus. The following variables were used:

  1. Demographics: Age, sex, race/ethnicity
  2. Dietary variables: Foods, food groups (as reported by the United States Department of Agriculture (USDA) method, further standardized to the Academy of Nutrition and Dietetics method for portion size and then divided into groups having inorganic phosphate additives or no inorganic phosphate additives), food weight (g), phosphorus (mg), dietary supplements
  3. Socioeconomic variables: education, family income
  4. Laboratory variables: serum creatinine, phosphorus; urine albumin, creatinine
  5. Clinical assessments: hypertension (proportion having blood pressure ≥140 millimeters of mercury (mmHg) diastolic or ≥90 mmHg systolic or taking antihypertensive medications); hyperglycemia (proportion having serum glucose >126 mg/dL or taking medications for diabetes); kidney function based on Chronic Kidney Disease Epidemiology Collaboration (2009) equation, evaluated in 15 milliliters/min/1.73m2 increments from <15 to >105; anthropometrics (BMI, kg/m2; obesity class I, II, III)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
20 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Serum creatinine

排除标准

  • Pregnancy
  • No dietary intake interview
  • Dietary intake interview not valid
  • Answered the question "Have you had dialysis in the past year?" as "Yes"

结局指标

主要结局

Serum phosphorus concentration

时间窗: approximately 24 hours

Serum phosphorus concentration on the day that 24-hour dietary recall was obtained (reflecting dietary intake the day prior to blood draw); measured in mg/dL

次要结局

  • Kidney function level(Baseline)

研究者

发起方
Linda W. Moore
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Linda W. Moore

Sponsor-Investigator/Principal Investigator

The Methodist Hospital Research Institute

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