Knee and Hip OsteoArthritis Long Term Assessment. Prevalence, Natural History, Prognosis Factor, Quality of Life, Health Care Consumption and Social Consequences of Symptomatic Knee and Hip Osteoarthritis in France
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 878
- 试验地点
- 6
- 主要终点
- Quality of life, patient reported outcome measures
研究概览
简要总结
The aim of the project is to assemble and to follow on a 10-year period a nationwide representative sample of lower limb OA patients.
General objectives: To document the natural history and to identify predictive factors of the evolution and consequences of hip and knee OA in terms of pain, functional disability, structural damage, quality of life, autonomy, medical and health care use and cost of disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •male and female aged between 40 and 75 years
- •symptomatic hip or knee, uni or bilateral OA with clinical diagnosis confirmed by a medical physician and satisfying ACR classification criteria
- •Representative of prevalent cases in France at the cohort set-up time
排除标准
- •presence of hip or knee joint replacement surgery
- •comorbidities severe enough to affect quality of life significantly or likely to induce a high health care consumption independently of OA
- •an history of osteotomy
- •Patello-femoral osteoarthritis without tibio-femoral osteoarthritis
- •Other joint diseases of the target joints
- •adult under legal protection or not able to consent
研究组 & 干预措施
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
干预措施: X-rays (Procedure)
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
干预措施: biological samples (Biological)
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
干预措施: medical information about osteoarthritis (Other)
结局指标
主要结局
Quality of life, patient reported outcome measures
时间窗: every year, up to 10 years
次要结局
- health care consumption(every year, up to 10 years)