NCT02544958Unknown不适用
The Efficacy and Safety of Erbium:Yttrium Aluminum Garnet Laser for Treatment of Enlarged Pores: A Pilot Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- The efficacy of Er:YAG laser in the treatment of enlarged pores (measurement of skin texture using UVA-light video camera)
研究概览
简要总结
To investigate the efficacy of Erbium:Yttrium aluminum garnet laser (Er:YAG) in the treatment of enlarged pores.
详细描述
- Enlarged pores are caused by multifactorial factors such as sex, genetics, aging, etc.
- The gold of the treatment is to recollagenesis of the dermis and resurfacing of the epidermis.
- Modalities that have been proved on their efficacy for enlarged pores treatment included topical retinoic acid, chemical peeling, intense pulsed light, radiofrequency device, laser such as Q-switched and Long Pulsed Neodymium-Doped Yttrium-Aluminum-Garnet (Nd:YAG) 1,064nm, Long pulse duration pulsed dye laser 595nm, etc.
- Er:YAG laser is an ablative laser which creates both recollagenesis and resurfacing. It ha been proved to be safe and effective in the treatment of atrophic acne scar.
- However, the efficacy of this laser for enlarged treatment has not yet been established.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Visible enlarged pores on both sides of the face
- •Fitzpatrick skin type 3-5
排除标准
- •Patients with lesions with any clinical suspicion of being pre-cancerous or skin malignancies of any kind
- •Patients who have photosensitive dermatoses
- •Pregnancy and lactation woman
- •Patients with wound infections (herpes, other) on the day of treatment
- •Patients with moderate and severe inflammatory acne, Immunosuppressed patients, history of vitiligo
- •Patients with unrealistic concerns/expectations and inability to do the appropriate post-operative care
研究组 & 干预措施
Er:YAG laser
Experimental
4 treatments of 1 month interval
干预措施: Er:YAG laser (Device)
结局指标
主要结局
The efficacy of Er:YAG laser in the treatment of enlarged pores (measurement of skin texture using UVA-light video camera)
时间窗: 1 month after 4 treatments
measurement of skin texture using UVA-light video camera
次要结局
- Hyperpigmentation side effect of Er:YAG laser in the treatment of enlarged pores(Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment)
- Hypopigmentation side effect of Er:YAG laser in the treatment of enlarged pores(Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment)
- Erythema side effect of Er:YAG laser in the treatment of enlarged pores(Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment)
- The patients satisfaction using Quartile grading scale of improvement(Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment)
研究者
Woraphong Manuskiatti, M.D.
Professor
Mahidol University
研究点 (1)
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