Comparing in vitro maturation of oocytes with in vitro fertilisation in women with an increased risk of ovarian hyperstimulation syndrome: A multicentre randomised controlled trial with non-randomised pilot study.

Jeroen Bosch Hospital (Netherlands)0 个研究点目标入组 450 人开始时间: 2010年5月27日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Women with Polycystic Ovarian Syndrome (PCOS) according to the Rotterdam Criteria (The Rotterdam
•European Society of Human Reproduction and Embryology [ESHRE] /American Society for Reproductive Medicine [ASRM] - Sponsored PCOS consensus workshop group, 2004) which not did achieve an ongoing pregnancy after ovulation induction (with clomiphene citrate or Laparoscopic Electrocoagulation of the Ovaries (LEO) and Recombinant Follicle Stimulating Hormone [rFSH])
•2. Women with an IVF or ICSI indication and increased risk for developing Ovarian Hyperstimulation Syndrome (OHSS) (history of OHSS or cycle cancellation for imminent OHSS)

•1. Woman or partner younger than 18 years and woman older than 38 years
•2. Unable to speak or read the Dutch language
•3. Medical contraindication for pregnancy or childbirth
•4. Positive serology for Hepatitis B, C or HIV
•5. Diminished ovarian reserve: early follicular serum FSH > 10 IU/l and/or poor response during earlier COH/IVF or COH/ICSI with = 150 IU rFSH/day
•6. Persisting ovarian cysts > 30 mm diameter

发起方

Jeroen Bosch Hospital (Netherlands)