跳至主要内容
临床试验/NCT03086590
NCT03086590已完成不适用

BODY COMPOSITION, PERIPHERAL MUSCULAR FORCE, KINEMATIC THORACIC-ABDOMINAL, VENTILATORY METABOLIC RESPONSE, DIAPHRAGM MOBILITY AND THICKNESS PREDICTION OF OBSTRUCTION LEVEL OF COPD?

Universidade Federal de Pernambuco1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2016年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Fat-free mass

研究概览

简要总结

To associate a lean mass, peripheral muscle strength, kinematic thoracic-abdominal, respiratory metabolic response, mobility and diaphragmatic thickness, verifying its relation with the obstruction level of COPD

详细描述

Individuals with COPD present restriction in their daily lives due to changes and bodily disorders promoted by the disease, such as changes in types of muscle fibers and chronic inflammatory process, causing a low level of physical activity and quality of life, besides being closely Related to the need for hospitalizations and increased mortality. A cross-sectional study with a convenience sample was performed at the Laboratory of Cardiopulmonary Physiotherapy of the Federal University of Pernambuco during the period from December 2016 to February 2018. As measurements of body composition were performed with a bio-balance scale, Evaluation of the peripheral muscle strength will be used the dynamometer, a load cell and electromyography, a kinematic thoracic-abdominal will be measured by optoelectronic plethysmography, a respiratory metabolic response will be verified during the 6-minute walk test using the gas analyzer, and for evaluation of mobility and diaphragmatic thickness are used on ultrasound associated with pneumotachograph.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
21 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Young adults, adults and elderly subjects

排除标准

  • Others respiratory diseases;
  • Heart diseases;
  • Those who are in some previous training program or rehabilitation;

结局指标

主要结局

Fat-free mass

时间窗: Baseline

Mass of the human body disregarding fat.

Quadriceps Force

时间窗: Baseline

Quadriceps muscle strength measured during maximum voluntary contraction.

Handgrip strength

时间窗: Baseline

Maximum voluntary manual holding force.

Total chest wall volume

时间窗: Baseline

Total volume resulting from the sum of the volume of the pulmonary compartment of the costal, abdominal gradient of the costal and abdominal beds.

Oxygen uptake

时间窗: Baseline

Consumption of oxygen during an effort.

Diaphragm mobility

时间窗: Baseline

It is the diaphragmatic movement from the end of the expiration until the end of the inspiration, being able to be realized in tidal volume or starting from the total pulmonary capacity.

Diaphragm thickness

时间窗: Baseline

Defined as a corpulence of the diaphragm muscle

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Rodrigo Viana Correia de Souza

Principal Investigator

Universidade Federal de Pernambuco

研究点 (1)

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