Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland - the STARR Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 800
- 试验地点
- 2
- 主要终点
- Mortality and morbidity of takotsubo syndrome
研究概览
简要总结
Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of the STARR study is to identify all cases of Takotsubo in Scotland since 2010 and assess its epidemiology and outcomes.
详细描述
Public Health Scotland will identify all patients centrally coded under codes I42.8 (Other cardiomyopathies), I42.9 (Cardiomyopathy, unspecified) and I51.8 (Other ill-defined heart diseases), using the Community Health Index (CHI) numbers from January 2010. All identified CHI numbers will be thereafter cross-checked with their clinical data at participating health boards to confirm a diagnosis of takotsubo cardiomyopathy and a registry of all confirmed Takotsubo cases will be established.
Clinical data will be collected for all Takotsubo patients retrospectively and prospectively. This will be compared to two contemporaneous gender and age matched control populations:
- a cohort of randomly selected individuals from the Scottish general population supplied by Public Health Scotland
- patients with myocardial infarction (extracted through collaboration with, the High-STEACS investigators, NCT01852123).
Electronic data linkage will be performed by Public Health Scotland to assess outcomes, prescribing and scores of prediction.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients diagnosed with Takotsubo cardiomyopathy
排除标准
- 未提供
研究组 & 干预措施
Takotsubo cardiomyopathy
All patients diagnosed with Takotsubo cardiomyopathy in Scotland since 2010.
Myocardial Infarction
An equal number of myocardial infarction patients in NHS Grampian since 2010.
结局指标
主要结局
Mortality and morbidity of takotsubo syndrome
时间窗: 13 years
To use a nation-wide cohort (and matched national-wide control populations) to establish the all-cause mortality and consequent all cause hospitalisation rates
次要结局
- Specific causes of mortality and morbidity of takotsubo syndrome(13 years)